. 2024 Oct 25;86(12):7408–7413. doi: 10.1097/MS9.0000000000002699

Table 2.

Bartter syndrome types.

Types	Affected gene	Laboratory findings	Clinical characteristics	References/ PMID
Type I	NKCC2	Hypokalemia, hypercalciuria, hypercalcemia, increased urinary potassium and chloride	Fetal polyuria, polyhydramnios, nephrocalcinosis, osteopenia	28723048^10,11
Type II	ROMK	Hyperkalemia at birth, then hypokalemia; hypercalciuria, increased urinary potassium and chloride, hyposthenuria	Nephrocalcinosis, failure to thrive, osteopenia, vomiting, diarrhea
Type III	CIC-Kb	Hypokalemia, metabolic alkalosis, increased urinary potassium and chloride, hypocalciuria or normocalciuria	Short stature, mental retardation, hypotensive
Type IVa	BSND	Hypokalemia, hyponatremia, hypochloremia, increased urinary sodium, potassium and chloride	Renal failure, sensorineural deafness, motor retardation
Type IVb	CIC-Ka, CIC-Kb
Type V	CaSr	Hypokalemia, metabolic alkalosis, hypocalcemia, hypercalciuria	Nephrocalcinosis, hypotension, seizures	¹¹ 33597159¹²