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. 1980 Nov 15;192(2):765–767. doi: 10.1042/bj1920765

Thyroid-hormone effects on ornithine decarboxylase.

E W Chideckel, S J Rozovski, E R Belur
PMCID: PMC1162395  PMID: 7236237

Abstract

We examined thyroidectomized, normal and hyperthyroid rats and found that ornithine decarboxylase activity was directly correlated with thyroid functional state in heart and liver and unaffected in brain, testes and spleen, phenomena that correlate with the known effect of thyroid hormone on protein synthesis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson T. R., Schanberg S. M. Effect of thyroxine and cortisol on brain ornithine decarboxylase activity and swimming behavior in developing rat. Biochem Pharmacol. 1975 Feb 15;24(4):495–501. doi: 10.1016/0006-2952(75)90136-7. [DOI] [PubMed] [Google Scholar]
  2. Antony P., Gibson K., Harris P. Ornithine decarboxylase activity in the isolated perfused rat heart. J Mol Cell Cardiol. 1976 Aug;8(8):589–597. doi: 10.1016/0022-2828(76)90045-6. [DOI] [PubMed] [Google Scholar]
  3. Aranda A., Montoya E., Herrera E. Effects of hypo- and hyper-thyroidism on liver composition, blood glucose, ketone bodies and insulin in the male rat. Biochem J. 1972 Jul;128(3):597–604. doi: 10.1042/bj1280597. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. BARKER S. B., KLITGAARD H. M. Metabolism of tissues excised from thyroxine-injected rats. Am J Physiol. 1952 Jul;170(1):81–86. doi: 10.1152/ajplegacy.1952.170.1.81. [DOI] [PubMed] [Google Scholar]
  5. DeMartino G. N., Goldberg A. L. Thyroid hormones control lysosomal enzyme activities in liver and skeletal muscle. Proc Natl Acad Sci U S A. 1978 Mar;75(3):1369–1373. doi: 10.1073/pnas.75.3.1369. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Kaye A. M., Icekson I., Lindner H. R. Stimulation by estrogens of ornithine and S-adenosylmethionine decarboxylases in the immature rat uterus. Biochim Biophys Acta. 1971 Oct;252(1):150–159. doi: 10.1016/0304-4165(71)90103-6. [DOI] [PubMed] [Google Scholar]
  7. Kobayashi Y., Kupelian J., Maudsley D. V. Ornithine decarboxylase stimulation in rat ovary by luteinizing hormone. Science. 1971 Apr 23;172(3981):379–380. doi: 10.1126/science.172.3981.379. [DOI] [PubMed] [Google Scholar]
  8. MICHELS R., CASON J., SOKOLOFF L. Thyroxine: effects on amino acid incorporation into protein in vivo. Science. 1963 Jun 28;140(3574):1417–1418. doi: 10.1126/science.140.3574.1417. [DOI] [PubMed] [Google Scholar]
  9. Mallette L. E., Exton J. H. Stimulation by insulin and glucagon of ornithine decarboxylase activity in perfused rat livers. Endocrinology. 1973 Sep;93(3):640–644. doi: 10.1210/endo-93-3-640. [DOI] [PubMed] [Google Scholar]
  10. Russell D., Snyder S. H. Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors. Proc Natl Acad Sci U S A. 1968 Aug;60(4):1420–1427. doi: 10.1073/pnas.60.4.1420. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Stevens L. The biochemical role of naturally occurring polyamines in nucleic acid synthesis. Biol Rev Camb Philos Soc. 1970 Feb;45(1):1–27. doi: 10.1111/j.1469-185x.1970.tb01073.x. [DOI] [PubMed] [Google Scholar]
  12. Yu S., Friedman Y., Richman R., Burke G. Altered thyroidal responsivity to thyrotropin induced by circulating thyroid hormones. A "short-loop" regulatory mechanism? J Clin Invest. 1976 Mar;57(3):745–755. doi: 10.1172/JCI108333. [DOI] [PMC free article] [PubMed] [Google Scholar]

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