TABLE 3.
Number of patients displaying clinically meaningful improvement in different baseline AEF performance categories and average test score change per month in maze, interference, and verbal fluency scores depending on the baseline performance category.
| Tests | Patients with clinically meaningful improvement | Changes in test scores (s or words/month) | |||
|---|---|---|---|---|---|
| N (%) | Average change | 95% CI | p Value | Number of patients and (testsNo) | |
| Maze | |||||
| All patients | 8/33 (24%) | −0.20 | −0.364 to –0.041 | 0.014 | 33 (128) |
| Normal | 0 /12 (0%) | −0.14 | −0.277 to −0.009 | 0.036 | 12 (44) |
| Mild impairment | 2/8 (25%) | −0.28 | −0.665 to 0.103 | 0.152 | 8 (31) |
| Severe impairment | 6/13 (46%) | −0.21 | −0.492 to 0.073 | 0.146 |
13 (53) |
| Interference | |||||
| All patients | 6/33 (18%) | −0.05 | −0.131 to 0.028 | 0.207 | 33 (130) |
| Normal | 1/12 (8%) | −0.04 | −0.095 to 0.022 | 0.225 | 12 (44) |
| Mild impairment | 0/8 (0%) | 0.08 | −0.114 to 0.274 | 0.418 | 8 (31) |
| Severe impairment | 5/13 (38%) | −0.11 | −0.225 to −0.013 | 0.028 | 13 (55) |
| Verbal fluency | |||||
| All patients | 3/33 (9%) | 0.03 | −0.003 to 0.064 | 0.079 | 33 (130) |
| Normal | 0 /12 (0%) | 0.04 | −0.021 to 0.100 | 0.201 | 12 (44) |
| Mild impairment | 0/8 (0%) | −0.02 | −0.060 to 0.021 | 0.347 | 8 (31) |
| Severe impairment | 3 /13 (23%) | 0.06 | −0.001 to 0.110 | 0.054 | 13 (55) |
Note: Bold values indicate statistically significant p values.
Abbreviations: AEF = attention and executive functions, CI = confidence interval.