Fig. 1.

Shows schematic of study conducted. This study was designed to identify the metabolites released through exercise in a control model and a PAH model. This will utilize Wistar Rats divided into four groups (i.e., a) Control (n ​= ​6), b) PAH (n ​= ​6) c) Exercise (n ​= ​6), and d) PAH ​+ ​Exercise (n ​= ​6). Animals were systematically randomized based on body weight stratification before PAH induction. PAH was induced using monocrotaline. Clinical signs were recorded daily, and body weight was measured weekly basis. Blood samples were drawn at baseline and after 5 weeks. At the end of the experiment, all rats were sacrificed.