Table 1. Patient characteristics and their treatment.
Characteristics | Patients with two interviewsn = 33 | Patients with OPATn = 190 | P value |
Gender | |||
Female sex, n (%) | 7 (21) | 68 (21) | 0.11 |
Male sex, n (%) | 26 (79) | 122 (64) | |
Age, median years (IQR) | 56 (43–71) | 57 (18–92) | 0.63 |
BMI, median kg/m2 (IQR) | 23 (22–25) | 25 (16–53) | 0.006 |
Charlson comorbidity index, median (IQR) | 3 (1–4) | 3 (0–13) | 0.48 |
OPAT setting | |||
Homecare-OPAT, n (%) | 12 (36) | 92 (48) | 0.16 |
Hospital-OPAT, n (%) | 14 (42) | 78 (41) | |
Self-administered, n (%) | 7 (21) | 20 (11) | |
Administration device | |||
Battery-operated pump, n (%) | 1 (3) | 11 (5.8) | 0.06 |
Elastomeric pump, n (%) | 18 (55) | 61 (32) | |
none, n (%) | 14 (42) | 118 (62) | |
Indication for OPAT (stratified by ICD-10 codes) | 0.22 | ||
Foreign body-associated infections,* n (%) | 8 (24) | 29 (15) | |
Other infections and parasitic diseases, n (%) | 5 (15) | 36 (19) | |
Urinary tract infections, n (%) | 4 (12) | 54 (28) | |
Hepatobiliary infections, n (%) | 4 (12) | 9 (5) | |
Infective endocarditis, n (%) | 4 (12) | 9 (5) | |
Osteoarticular infections, n (%) | 3 (9) | 16 (8) | |
Central nervous system infections, n (%) | 3 (9) | 21 (11) | |
Respiratory tract infections, n (%) | 1 (3) | 7 (4) | |
Ear, nose and throat infections, n (%) | 1 (3) | 4 (2) | |
Intraabdominal infections, n (%) | 0 (0) | 5 (3) | |
OPAT duration, median days (IQR) | 15 (6–27) | 9 (6–19) | 0.25 |
Adverse events, line-related, n (%) | 2 (6) | 7 (3.7) | 0.53 |
Adverse events, drug-related, n (%) | 3 (9) | 30 (16) | 0.82 |
Includes prosthetic joint infections, vascular graft infections, breast implant infections.
BMIbody mass indexICDInternational Classification of DiseasesOPATOutpatient parenteral antimicrobial therapy