Table 2.

Shows WHO diagnostic criteria for polycythemia vera (PV).

Major criteria
1- Hemoglobin >18.5 g/dL in men, 16.5 g/dL in women, or other evidence of increased red cell volume (RCV)
2- Presence of JAK2V617F or other functionally similar mutation
Minor criteria
1- Bone marrow biopsy specimen showing hypercellularity for age
2- Serum erythropoietin (EPO) level below the reference range for normal
3- Endogenous erythroid colony formation in vitro