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. 2024 Nov 23;45:201–230. doi: 10.1016/j.bioactmat.2024.11.021

Table 1.

Examples of CQA in 3D bioprinting.

Approach Examples of CQA
Forming-based Printability Extrudability, filament formation, shape fidelity
Rheological properties Shear-thinning, viscoelasticity, yield stress, constitutive model
Gelation properties Gelation time, gel fraction
Function-based Transport properties Effective mass diffusion rate, vascularization
Mechanical properties Mechanical response: Young's modulus, response curve, constitutive model, strength
Degradation properties: degradation rate
Swelling properties: swelling rate
Function-based Biological properties [41] Gene expression: cell differentiation and phenotype, cell health, genomic stability
Protein expression: matrix production, cell differentiation and phenotype, cell health
Cell metabolism: nutrient and waste analysis, cell signaling, cellular products, cell health
Cell properties: viability, morphology, motility, confluence, cell number, cell health
Tissue properties: morphology, function