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. 2024 Oct 28;6(1):100375. doi: 10.1016/j.xhgg.2024.100375

Table 1.

Putative target genes identified by co-localization analysis between AS-associated loci and eQTLs in NK cells

Lead GWAS variant p value GWAS Putative target gene Posterior probability of shared causal variant Quantification method eQTL study
rs27529 1.24E−40 IGAS ERAP1 0.99186 microarray Gilchrist et al. (2021)32
rs6759298 2.07E−38 IGAS B3GNT2 0.97245 RNA-seq Schmiedel et al. (2018)31
rs1128905 3.17E−10 IGAS ENTR1 0.8207 microarray Gilchrist et al. (2021)32
rs1860545 8.66E−10 IGAS TNFRSF1A 0.99673 RNA-seq Schmiedel et al. (2018)31
rs11065898 5.41E−8 IGAS TMEM116 0.87563 microarray Gilchrist et al. (2021)32
rs9619386 4.42E−7 IGAS UBE2L3 0.96397 microarray Gilchrist et al. (2021)32
rs1250542 2.07E−6 IGAS ZMIZ1 0.87272 microarray Gilchrist et al. (2021)32
rs1250542 2.07E−6 IGAS ZMIZ1 0.83268 RNA-seq Schmiedel et al. (2018)31
rs952594 2.08E−6 IGAS APEH 0.75689 microarray Gilchrist et al. (2021)32
rs952594 2.08E−6 IGAS RBM6 0.91981 RNA-seq Schmiedel et al. (2018)31
rs952594 2.08E−6 IGAS UBA7 0.94237 microarray Gilchrist et al. (2021)32
rs952594 2.08E−6 IGAS UBA7 0.8851 RNA-seq Schmiedel et al. (2018)31
rs6565217 2.82E−6 IGAS AC135050.3 0.91556 RNA-seq Schmiedel et al. (2018)31
rs6565217 2.82E−6 IGAS STX4 0.94653 RNA-seq Schmiedel et al. (2018)31
rs7191548 3.13E−6 IGAS EIF3CL 0.7822 microarray Gilchrist et al. (2021)32
rs7191548 3.13E−6 IGAS NPIPB8 0.97545 microarray Gilchrist et al. (2021)32
rs7191548 3.13E−6 IGAS SGF29 0.85225 microarray Gilchrist et al. (2021)32
rs7191548 3.13E−6 IGAS TUFM 0.82246 microarray Gilchrist et al. (2021)32
rs7191548 3.13E−6 IGAS TUFM 0.95694 RNA-seq Schmiedel et al. (2018)31
rs6583441 3.84E−6 IGAS IKZF1 0.96244 RNA-seq Schmiedel et al. (2018)31
rs4690326 6.49E−6 IGAS DGKQ 0.91883 microarray Gilchrist et al. (2021)32
rs4690326 6.49E−6 IGAS DGKQ 0.89989 RNA-seq Schmiedel et al. (2018)31
rs4690326 6.49E−6 IGAS IDUA 0.98988 microarray Gilchrist et al. (2021)32
rs4690326 6.49E−6 IGAS SLC49A3 0.801 RNA-seq Schmiedel et al. (2018)31
rs26481 9.17E−6 UK Biobank CAST 0.95638 microarray Gilchrist et al. (2021)32
rs26481 9.17E−6 UK Biobank ERAP1 0.95565 microarray Gilchrist et al. (2021)32
rs2236167 3.57E−5 IGAS PPP2R3C 0.9491 microarray Gilchrist et al. (2021)32