Table 2.
COX regression analysis of OS in patients with gallbladder cancer.
| Item | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR(95%CI) | P | HR(95%CI) | P | |
| Age | ||||
| <60 | Reference | |||
| ≥60 | 0.774(0.572-1.048) | 0.166 | ||
| Gender | ||||
| Female | Reference | |||
| Male | 0.992(0.730-1.347) | 0.968 | ||
| Race | ||||
| Black | Reference | |||
| Others | 0.991(0.564-1.741) | 0.979 | ||
| White | 1.067(0.711-1.601) | 0.791 | ||
| Marital | ||||
| Married | Reference | Reference | ||
| Single | 1.100(1.066-1.579) | 0.043 | 1.056(0.601-1.414) | 0.757 |
| Histologic | ||||
| Others | Reference | |||
| Adeno | 0.876(0.603-1.272) | 0.562 | ||
| Grade | ||||
| Grade I-II | Reference | |||
| Grade III-IV | 1.100(0.817-1.482) | 0.596 | ||
| Clinical T stage | ||||
| T1-2 | Reference | |||
| T3-4 | 1.243(0.856-1.805) | 0.336 | ||
| Clinical N stage | ||||
| N0 | Reference | |||
| N1 | 0.979(0.726-1.319) | 0.909 | ||
| N2 | 0.821(0.441-1.527) | 0.602 | ||
| AJCC | ||||
| III | Reference | Reference | ||
| IV | 1.758(1.311-2.358) | <0.001 | 1.91(1.408-2.593) | <0.001 |
| LND | ||||
| 0 | Reference | Reference | ||
| 1-3 | 0.529(0.367-0.763) | 0.004 | 0.494(0.331-0.739) | 0.004 |
| ≥4 | 0.494(0.334-0.730) | 0.002 | 0.453(0.295-0.695) | 0.002 |
| Radiation | ||||
| No | Reference | |||
| Yes | 0.938(0.681-1.293) | 0.745 | ||
| Tumor size | ||||
| <5cm | Reference | Reference | ||
| ≥5cm | 1.911(1.327-2.751) | 0.003 | 2.042(1.402-2.975) | 0.002 |
| Unknown | 1.304(0.927-1.835) | 0.199 | 1.195(0.835-1.710) | 0.412 |
| Treatment | ||||
| groupA | Reference | Reference | ||
| groupB | 1.909(1.417-2.571) | 0.003 | 2.322(1.680-3.209) | <0.001 |