Table 1.
Patient Characteristics at Baseline in Groups 1–4
| Group 1 (n=125) |
Group 2 (n=102) |
Group 3 (n=395) |
Group 4 (n=384) |
P value | |
|---|---|---|---|---|---|
| Age (years) | 63±11 | 65±10 | 68±10 | 70±9 | <0.0001 |
| Sex, male (%) | 82 | 79 | 74 | 79 | 0.119 |
| BMI (%) | 25.1±3.0 | 24.8±3.6 | 24.1±4.3 | 23.8±3.5 | 0.003 |
| SBP (mmHg) | 138±30 | 133±37 | 134±27 | 130±22 | 0.113 |
| DBP (mmHg) | 73±15 | 71±20 | 72±15 | 70±14 | 0.113 |
| Pulse rate (/min) | 75±16 | 66±19 | 73±15 | 73±13 | <0.001 |
| Smoking history (%) | 65 | 67 | 61 | 65 | 0.454 |
| Family history (%) | 18 | 17 | 14 | 13 | 0.493 |
| UCG-LVEF (%) | 59±14 | 60±13 | 59±14 | 60±13 | 0.405 |
| Blood sampling tests | |||||
| TC (mg/dL) | 227±41 | 170±26 | 196±29 | 144±20 | <0.0001 |
| TG (mg/dL) | 241±41 | 288±121 | 106±36 | 100±36 | <0.0001 |
| HDL-C (mg/dL) | 43±11 | 40±10 | 47±12 | 47±13 | <0.0001 |
| LDL-C (mg/dL) | 136±35 | 73±18 | 127±26 | 77±15 | <0.0001 |
| LDL-C/HDL-C ratio | 3.34 | 1.97 | 2.88 | 1.78 | <0.0001 |
| Non-HDL-C (mg/dL) | 184±40 | 131±28 | 149±27 | 97±17 | <0.0001 |
| Cr (mg/dL) | 1.1±0.5 | 1.0±0.3 | 1.0±0.5 | 1.0±0.5 | 0.043 |
| eGFR(mL/min) | 65±34 | 86±25 | 83±33 | 79±27 | 0.063 |
| UA (mg/dL) | 6.0±1.4 | 5.9±1.3 | 5.5±1.5 | 5.6±1.5 | 0.002 |
| HbA1c (%) | 7.5±1.3 | 7.3±1.3 | 7.4±1.3 | 7.3±1.2 | 0.067 |
| Prior diseases/complicated diseases | |||||
| ASO (%) | 12 | 8.8 | 10 | 14 | 0.301 |
| Prior CVA (%) | 17 | 11 | 16 | 14 | 0.468 |
| Hypertension (%) | 72 | 79 | 77 | 80 | 0.354 |
| Dyslipidemia (%) | 95 | 97 | 87 | 88 | <0.0001 |
| SAP/UAP/AMI/OMI/SMI (%) | 36/18/27/2.1/18 | 37/12/22/0/28 | 28/12/46/1.5/13 | 34/10/33/2.4/20 | |
AMI, acute myocardial infarction; ASO, arteriosclerosis obliterans; BMI, body mass index; CABG, coronary artery bypass graft; Cr, creatinine; CVA, cerebrovascular accident; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HbA1c, hemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; LVEF, left ventricular ejection fraction; MI, myocardial infarction; OMI, old myocardial infarction; PCI, percutaneous coronary intervention; SAP, stable angina pectoris; SBP, systolic blood pressure; SMI, subsequent myocardial infarction; TC, total cholesterol; TG, triglycerides; UA, uric acid; UAP, unstable angina pectoris; UCG, ultrasound cardiography.