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. 2024 Nov 25;15:1456150. doi: 10.3389/fimmu.2024.1456150

Figure 2.

Figure 2

Cox regression analysis and correlation analysis indicated that baseline pain was the independent prognostic factor for ICIs treatment. (A) Nomogram construction based on bone metastasis and pain before PSM. (B) KM survival analysis showed that the prognosis of low risk patients better than high risk patients (HR=1.73, 95%CI: 1.26-2.38, p=5.8e-4). (C) The AUC under the ROC curve with 1 year 0.69, 3 year 0.62 and 5year 0.62. (D) Nomogram construction based on age, liver metastasis, bone metastasis, platelets, dNLR and pain after PSM. (E) KM survival analysis showed that the prognosis of low risk patients better than high risk patients (HR=2.41, 95%CI: 1.51-3.86, p=1.6e-4). (F) The AUC under the ROC curve with 1 year 0.80, 3 year 0.73 and 5year 0.80. (G) Correlation analysis showed that NRS score was positively correlated with monocytes, neutrophils, leukocytes and platelets, and negatively correlated with lymphocytes.