Table 4.
Univariate cox analysis and Multivariate cox analysis after PSM.
| Variables | Univariate | Multivariate | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| β | S. E | t | P | HR (95%CI) | β | S. E | t | P | HR (95%CI) | |
| Age | 0.04 | 0.01 | 2.52 | 0.012 | 1.04 (1.01 - 1.07) | 0.08 | 0.02 | 3.35 | <.001 | 1.08 (1.03 - 1.13) |
| Weight | -0.02 | 0.01 | -1.28 | 0.201 | 0.98 (0.96 - 1.01) | -0.04 | 0.12 | -0.31 | 0.759 | 0.96 (0.77 - 1.21) |
| Height | 0.02 | 0.02 | 0.97 | 0.331 | 1.02 (0.98 - 1.05) | 0.01 | 0.07 | 0.10 | 0.917 | 1.01 (0.88 - 1.15) |
| BSA | -0.38 | 0.87 | -0.44 | 0.661 | 0.68 (0.13 - 3.73) | 4.50 | 9.10 | 0.49 | 0.621 | 89.62 (0.00 - 4947835799.89) |
| Neutrophils | 0.03 | 0.03 | 0.84 | 0.400 | 1.03 (0.96 - 1.10) | -1.22 | 0.72 | -1.70 | 0.089 | 0.30 (0.07 - 1.20) |
| Lymphocytes | -0.27 | 0.18 | -1.49 | 0.135 | 0.77 (0.54 - 1.09) | -1.94 | 1.00 | -1.93 | 0.054 | 0.14 (0.02 - 1.03) |
| Leukocyte | 0.02 | 0.03 | 0.57 | 0.568 | 1.02 (0.96 - 1.08) | 1.09 | 0.66 | 1.64 | 0.100 | 2.96 (0.81 - 10.84) |
| Platelets | 0.00 | 0.00 | 0.95 | 0.343 | 1.00 (1.00 - 1.00) | 0.01 | 0.00 | 2.74 | 0.006 | 1.01 (1.01 - 1.02) |
| Monocytes | 0.31 | 0.33 | 0.94 | 0.348 | 1.36 (0.72 - 2.58) | 0.79 | 1.01 | 0.78 | 0.438 | 2.20 (0.30 - 16.05) |
| NLR | 0.09 | 0.03 | 2.77 | 0.006 | 1.09 (1.03 - 1.17) | 0.01 | 0.13 | 0.09 | 0.926 | 1.01 (0.79 - 1.30) |
| Dnlr | 0.17 | 0.07 | 2.38 | 0.017 | 1.18 (1.03 - 1.36) | 1.18 | 0.46 | 2.57 | 0.010 | 3.27 (1.33 - 8.04) |
| PLR | 0.01 | 0.00 | 2.16 | 0.030 | 1.01 (1.01 - 1.01) | -0.00 | 0.01 | -0.70 | 0.484 | 1.00 (0.99 - 1.01) |
| LMR | -0.11 | 0.06 | -1.71 | 0.087 | 0.90 (0.80 - 1.02) | 0.11 | 0.11 | 1.01 | 0.312 | 1.12 (0.90 - 1.39) |
| SII | 0.01 | 0.00 | 2.62 | 0.009 | 1.01 (1.01 - 1.01) | -0.00 | 0.00 | -1.95 | 0.051 | 1.00 (1.00 - 1.00) |
| Gender | ||||||||||
| 1 | Ref | Ref | ||||||||
| 2 | 0.05 | 0.29 | 0.16 | 0.873 | 1.05 (0.59 - 1.85) | 0.53 | 0.76 | 0.70 | 0.486 | 1.69 (0.38 - 7.47) |
| Alcohol | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | -0.19 | 0.27 | -0.68 | 0.495 | 0.83 (0.49 - 1.42) | 0.35 | 0.53 | 0.67 | 0.501 | 1.43 (0.51 - 4.00) |
| ECOG | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | 0.16 | 0.25 | 0.63 | 0.527 | 1.17 (0.72 - 1.90) | 0.49 | 0.40 | 1.24 | 0.215 | 1.63 (0.75 - 3.54) |
| 2 | 0.51 | 0.48 | 1.06 | 0.291 | 1.66 (0.65 - 4.27) | 0.58 | 1.08 | 0.54 | 0.592 | 1.79 (0.21 - 14.89) |
| 3 | 0.00 | NA | NA (NA - NA) | 0.00 | NA | NA (NA - NA) | ||||
| Smoke | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | -0.00 | 0.26 | -0.00 | 0.999 | 1.00 (0.61 - 1.65) | -0.15 | 0.64 | -0.24 | 0.809 | 0.86 (0.25 - 3.00) |
| HBV | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | 0.10 | 0.52 | 0.19 | 0.849 | 1.10 (0.40 - 3.03) | 0.66 | 0.73 | 0.90 | 0.366 | 1.93 (0.46 - 8.00) |
| Tumor | ||||||||||
| 1 | Ref | Ref | ||||||||
| 2 | 0.33 | 0.36 | 0.93 | 0.354 | 1.39 (0.69 - 2.80) | -0.16 | 0.78 | -0.20 | 0.842 | 0.86 (0.19 - 3.94) |
| Pathology | ||||||||||
| 1 | Ref | Ref | ||||||||
| 2 | -0.13 | 0.28 | -0.46 | 0.645 | 0.88 (0.51 - 1.52) | 0.50 | 0.46 | 1.07 | 0.283 | 1.64 (0.66 - 4.06) |
| 3 | 0.28 | 0.30 | 0.93 | 0.350 | 1.32 (0.74 - 2.35) | 0.20 | 0.58 | 0.35 | 0.729 | 1.22 (0.39 - 3.80) |
| T | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | -0.96 | 0.52 | -1.84 | 0.066 | 0.38 (0.14 - 1.07) | -0.31 | 0.80 | -0.38 | 0.701 | 0.74 (0.15 - 3.52) |
| 2 | -0.26 | 0.40 | -0.64 | 0.519 | 0.77 (0.35 - 1.69) | -0.75 | 0.62 | -1.21 | 0.228 | 0.47 (0.14 - 1.60) |
| 3 | 0.05 | 0.42 | 0.12 | 0.907 | 1.05 (0.46 - 2.40) | 0.30 | 0.63 | 0.48 | 0.632 | 1.35 (0.40 - 4.61) |
| 4 | 0.00 | 0.31 | 0.01 | 0.990 | 1.00 (0.54 - 1.85) | -0.01 | 0.49 | -0.02 | 0.985 | 0.99 (0.38 - 2.59) |
| N | ||||||||||
| 0 | Ref | Ref | ||||||||
| 2 | -0.09 | 0.36 | -0.25 | 0.803 | 0.91 (0.45 - 1.84) | -0.06 | 0.56 | -0.10 | 0.921 | 0.95 (0.32 - 2.82) |
| 3 | -0.16 | 0.35 | -0.46 | 0.645 | 0.85 (0.43 - 1.69) | -0.87 | 0.61 | -1.43 | 0.152 | 0.42 (0.13 - 1.38) |
| M | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | 0.07 | 0.31 | 0.24 | 0.807 | 1.08 (0.59 - 1.96) | -0.32 | 0.53 | -0.59 | 0.552 | 0.73 (0.26 - 2.07) |
| Lung metastasis | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | 0.30 | 0.24 | 1.24 | 0.215 | 1.34 (0.84 - 2.15) | 0.84 | 0.47 | 1.76 | 0.078 | 2.31 (0.91 - 5.85) |
| Liver metastasis | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | 0.19 | 0.34 | 0.56 | 0.577 | 1.21 (0.62 - 2.36) | 1.35 | 0.59 | 2.29 | 0.022 | 3.88 (1.22 - 12.34) |
| Bone metastasis | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | 0.68 | 0.25 | 2.73 | 0.006 | 1.98 (1.21 - 3.24) | 1.30 | 0.47 | 2.78 | 0.005 | 3.66 (1.47 - 9.16) |
| Brain metastasis | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | 0.22 | 0.29 | 0.75 | 0.452 | 1.24 (0.71 - 2.18) | 0.01 | 0.51 | 0.03 | 0.980 | 1.01 (0.37 - 2.76) |
| Adrenal metastasis | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | 0.40 | 0.29 | 1.37 | 0.172 | 1.49 (0.84 - 2.65) | -0.29 | 0.50 | -0.57 | 0.567 | 0.75 (0.28 - 2.01) |
| Other Lymph node metastasis | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | -0.24 | 0.30 | -0.80 | 0.426 | 0.78 (0.43 - 1.42) | -0.00 | 0.50 | -0.01 | 0.995 | 1.00 (0.37 - 2.66) |
| Pleura metastasis | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | 0.40 | 0.29 | 1.38 | 0.167 | 1.50 (0.84 - 2.65) | 0.34 | 0.45 | 0.76 | 0.448 | 1.40 (0.58 - 3.37) |
| Meningeal metastasis | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | -17.07 | 3113.62 | -0.01 | 0.996 | 0.00 (0.00 - Inf) | -17.61 | 3344.31 | -0.01 | 0.996 | 0.00 (0.00 - Inf) |
| NRS | ||||||||||
| 0 | Ref | Ref | ||||||||
| 1 | 0.40 | 0.24 | 1.68 | 0.093 | 1.49 (0.94 - 2.36) | 0.98 | 0.36 | 2.74 | 0.006 | 2.66 (1.32 - 5.37) |
Bold values: P value<0.05.