TABLE 4.
Overall test metrics for autoimmune screening panel.
| Statistics | Results | |
|---|---|---|
| All patients | Red flag symptoms | |
| Sensitivity, % (95% CI) | 75.0 (19.4–99.4) | 75 (19.4–99.4) |
| Specificity, % (95% CI) | 72.1 (65.5–78.1) | 100.0 (63.1–100.0) |
| Positive likelihood ratio (95% CI) | 2.7 (1.4–4.9) | NA |
| Negative likelihood ratio (95% CI) | 0.4 (0.1–1.9) | 0.25 (0.05–1.36) |
| AID prevalence, % | 1.9 | 33.3 |
| Positive predictive value, % (95% CI) | 4.9 (2.8–8.7) | 100.0 (29.2–100.0) |
| Negative predictive value, % (95% CI) | 99.3 (96.5–99.9) | 88.9 (59.4–97.8) |
| Accuracy, % | 72.2 (65.6–78.1) | 91.7 (61.5–99.8) |
Abbreviations: AID, autoimmune disease; CI, confidence interval; NA, not applicable.