Figure 2.

Ligand-receptor interactions between MSI-H cells and immune cells in scCRC dataset. (A, B) PD1 and PD-L1 expression in MSI-H, MSS, and CD8+ T cells. (C) Percentage of PD-L1 expression cells in MSI-H cluster and MSS cluster. (D, E) Ligand-receptor interaction from MSI-H cells to immune cells (D), and from immune cells to MSI-H cells (E). Cell types are denoted by colors, arrows signify communication direction, and arrow thickness symbolizes communication probabilities. (F, G) Communication probability of ligand-receptor pairs between MSI-H and immune cells, and between MSS and immune cells. Labels on x-axis labels indicate the communication direction. (H) Density of gene expression mediating the crosstalk.