Table 4.
Comparison of patient features by surgery before and after propensity score matching (PSM)
| Characteristics | Unmatched Cohort | 1:1 propensity score matched (PSM) Cohort | ||||
|---|---|---|---|---|---|---|
|
|
|
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| Surgery not given | Surgery | Unadjusted | Surgery not given | Surgery | PSM-adjusted | |
|
|
|
|||||
| N=11478 (%) | N=689 (%) | P value | N=685 (%) | N=685 (%) | P value | |
| Age | *** | 0.87 | ||||
| < 50 | 711 (6.19) | 62 (9.00) | 55 (8.03) | 61 (8.91) | ||
| 50-59 | 2710 (23.61) | 197 (28.59) | 201 (29.34) | 195 (28.47) | ||
| 60-69 | 4160 (36.24) | 267 (38.75) | 279 (40.73) | 266 (38.83) | ||
| 70-79 | 2916 (25.41) | 140 (20.32) | 128 (18.69) | 140 (20.44) | ||
| ≥ 80 | 981 (8.55) | 23 (3.34) | 22 (3.21) | 23 (3.36) | ||
| Sex | 0.83 | 0.59 | ||||
| Female | 5389 (46.95) | 327 (47.46) | 337 (49.20) | 326 (47.59) | ||
| Male | 6089 (53.05) | 362 (52.54) | 348 (50.80) | 359 (52.41) | ||
| Race | ** | 0.78 | ||||
| White | 8824 (76.88) | 569 (82.58) | 561 (81.90) | 565 (82.48) | ||
| Black | 1412 (12.30) | 66 (9.58) | 63 (9.20) | 66 (9.64) | ||
| Others | 1242 (10.82) | 54 (7.84) | 61 (8.91) | 54 (7.88) | ||
| Marriage status | ** | 0.72 | ||||
| Married | 6185 (53.89) | 412 (59.80) | 413 (60.29) | 409 (59.71) | ||
| Divorced/Separated | 1687 (14.70) | 91 (13.21) | 78 (11.39) | 91 (13.28) | ||
| Single | 2168 (18.89) | 130 (18.87) | 132 (19.27) | 129 (18.83) | ||
| Widowed | 1438 (12.53) | 56 (8.13) | 62 (9.05) | 56 (8.18) | ||
| Months from diagnosis to therapy | *** | 0.96 | ||||
| 0 month | 4417 (38.48) | 387 (56.17) | 382 (55.77) | 384 (56.06) | ||
| ≥ 1 month | 5530 (48.18) | 302 (43.83) | 303 (44.23) | 301 (43.94) | ||
| Pathological type | *** | 0.36 | ||||
| Adenocarcinoma | 6707 (58.43) | 419 (60.81) | 437 (63.80) | 416 (60.73) | ||
| Squamous cell | 1553 (13.53) | 88 (12.77) | 73 (10.66) | 88 (12.85) | ||
| Small cell | 1164 (10.14) | 25 (3.63) | 33 (4.82) | 25 (3.65) | ||
| Large cell | 227 (1.98) | 30 (4.35) | 22 (3.21) | 30 (4.38) | ||
| Others | 1827 (15.92) | 127 (18.43) | 120 (17.52) | 126 (18.39) | ||
| Grade | *** | 0.46 | ||||
| Grade I | 388 (3.38) | 26 (3.77) | 35 (5.11) | 25 (3.65) | ||
| Grade II | 2522 (21.97) | 215 (31.20) | 204 (29.78) | 214 (31.24) | ||
| Grade III | 7622 (66.41) | 412 (59.80) | 404 (58.98) | 411 (60.00) | ||
| Grade IV | 946 (8.24) | 36 (5.22) | 42 (6.13) | 35 (5.11) | ||
| T Stage | *** | 0.84 | ||||
| T1 | 1099 (9.57) | 127 (18.43) | 111 (16.20) | 123 (17.96) | ||
| T2 | 3162 (27.55) | 270 (39.19) | 279 (40.73) | 270 (39.42) | ||
| T3 | 2895 (25.22) | 157 (22.79) | 156 (22.77) | 157 (22.92) | ||
| T4 | 4322 (37.65) | 135 (19.59) | 139 (20.29) | 135 (19.71) | ||
| N Stage | *** | 0.71 | ||||
| N0 | 2515 (21.91) | 330 (47.90) | 326 (47.59) | 326 (47.59) | ||
| N1 | 1068 (9.30) | 114 (16.55) | 112 (16.35) | 114 (16.64) | ||
| N2 | 5491 (47.84) | 203 (29.46) | 214 (31.24) | 203 (29.64) | ||
| N3 | 2404 (20.94) | 42 (6.10) | 33 (4.82) | 42 (6.13) | ||
| Chemotherapy | ** | 0.09 | ||||
| No/unknown | 4983 (43.41) | 263 (38.17) | 230 (33.58) | 261 (38.10) | ||
| Yes | 6495 (56.59) | 426 (61.83) | 455 (66.42) | 424 (61.90) | ||
| Radiotherapy | * | 0.55 | ||||
| No/unknown | 2787 (24.28) | 142 (20.61) | 149 (21.75) | 139 (20.29) | ||
| Yes | 8691 (75.72) | 547 (79.39) | 536 (78.25) | 546 (79.71) | ||
| Bone metastasis | *** | 1.00 | ||||
| No | 7718 (67.24) | 597 (86.65) | 592 (86.42) | 593 (86.57) | ||
| Yes | 3760 (32.76) | 92 (13.35) | 93 (13.58) | 92 (13.43) | ||
| Liver metastasis | *** | 0.45 | ||||
| No | 9537 (83.09) | 653 (94.78) | 656 (95.77) | 649 (94.74) | ||
| Yes | 1941 (16.91) | 36 (5.22) | 29 (4.23) | 36 (5.26) | ||
| Lung metastasis | *** | 0.78 | ||||
| No | 8465 (73.75) | 623 (90.42) | 623 (90.95) | 619 (90.36) | ||
| Yes | 3013 (26.25) | 66 (9.58) | 62 (9.05) | 66 (9.64) | ||
*P < 0.05, **P < 0.01, ***P < 0.001. PSM, propensity score matching.