FIGURE 1.

Statistically significant variables associated with (A) MACE and (B) malignancy. The primary analyses without laboratory tests included as risk factors are shown. Statistical significance was defined as p < 0.05. The covariate assessment window for sex and age was the index date; for NSAIDs and glucocorticoids, it was the period from 3 months prior to the index date; for comorbidities and prior X‐ray examination, it was the period from 1 year prior to the index date; and for history of malignancy, it was the period from the initial date in the database to 1 year prior to the index date. CI, confidence interval; HR, hazard ratio; MACE, major adverse cardiovascular events; NSAID, non‐steroidal anti‐inflammatory drug.