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Neutrophil elastase (NE) and myeloperoxidase (MPO) extracellular vesicle (EV) content. Changes in EV cargo expressed as: a) NE/flotillin-1 (FLOT1) and b) MPO/FLOT1 ratios with therapy for PEx. Black horizontal lines are medians and vertical lines are interquartile ranges. **: p<0.01, Mann–Whitney test.
