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. 2024 Oct 21;13(4):228–231. doi: 10.4103/gmit.gmit_2_24

Table 5.

A summary overview comparing each type of adhesion barriers (5–7)

Adhesion barrier types Materials Clinical evidence Usability
Solid membranes Oxidized regenerated cellulose membrane Shown to be more effective than Seprafilm® in some pelvic operations when completely hemostatic
Reported to have no significant anti-adhesion effect in certain animal models Significantly reduced the overall incidence of adhesions
Applied more easily than Seprafilm because of its flexibility and good adhesiveness on wounds
Solution (not available in Japan) Icodextrin solution Reduced adhesion in several procedures
Adverse effects were reported such as extravasation, transient labial edema, incidence of small-bowel obstruction
Solution can diffuse throughout the peritoneal cavity
Hydrogel Gel-based dextrin polymer Reduced incidence and severity of peritoneal adhesion in laparotomy Easily applied during laparoscopy using a dedicated sprayer