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. 2024 Nov 4;14(19):7488–7504. doi: 10.7150/thno.102647

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Dusp1 is associated with the prognosis of septic patients. A. Gene Ontology Enrichment Analysis results for the differentially expressed genes between the control and SCM groups within the cardiomyocyte subpopulation, identifying key biological processes, molecular functions, and cellular components associated with the observed transcriptomic differences. B-C. GSEA (Gene Set Enrichment Analysis) plots highlighting the related pathways in the control and SCM groups within the cardiomyocyte subpopulation. D-F. Correlation analysis investigating the relationship between Dusp1 expression levels and the activity of OXPHOS, apoptosis, and inflammatory response pathways within the cardiomyocyte subpopulation of the SCM group. G. ssGSEA algorithm was used to score the "Cardiac muscle contraction" gene set in cardiomyocyte subpopulations of septic cardiomyopathy mouse heart samples. H. The GSE65682 dataset was used to analyze the role of Dusp1/MAPK in the prognosis of septic patients.