Table 3. Statistical analysis of qPCR results: P-values. Statistically significant values (P < 0.05) are highlighted in bold.

Group	Genetic features			MYC	VCAM1	MCL1	CXCR4	CCL4
	IGHV	TP53	NOTCH1	CMC-PEG gel vs. Conventional culture
All	Both	Both	Both	0.0115 (incl. Gr4) 0.1887 (excl. Gr4)	0.6788 (incl. Gr4) 6.57E–11 (excl. Gr4)	0.0053	3.97E–05	0.1875
Gr1	Unmut	WT	Mut	0.2437	3.38E–05	0.1843	0.1119	0.1093
Gr2	Unmut	Mut	Unmut	0.0025	6.68E–06	0.0059	0.0032	0.8153
Gr3	Unmut	WT	Mut	0.7315	0.0490	0.8690	0.1361	0.7431
Gr4	Mut	WT	WT	2.37E–06	6.04E–06	0.7698	0.6596	0.2011
Gr5	Unmut	WT	WT	0.0293	0.0019	0.0441	9.39E–06	0.2758
Group	IGHV	TP53	NOTCH1	Collagen scaffolds vs. Conventional culture
All	Both	Both	Both	0.7629	0.0043	0.0060	0.0136	0.0003
Gr1	Unmut	WT	Mut	0.9451	6.31E–05	0.0293	0.2287	0.5678
Gr2	Unmut	Mut	Unmut	0.0057	0.0016	0.0877	0.4964	0.0032
Gr3	Unmut	WT	Mut	0.2759	0.0924	0.0019	0.0010	0.9811
Gr4	Mut	WT	Wt	0.4025	0.1548	0.3524	0.9599	0.0493
Gr5	Unmut	WT	Wt	1.66E–06	0.0122	0.1402	0.1891	0.0496

Note:

Unmut, unmutated; Mut, mutated; WT, wild type; Gr, group; incl., including; excl., excluding. N = 3 biological replicates for each culture.