Fig. 2.

The number (A) and the spreading area (B) of rat aortic VSMCs on day 1 after seeding on unmodified type I collagen (Col) or with Col exposed to extracts from mast cells cultured under normoxia (Norm) or hypoxia (Hyp). Mean ± SEM from 9–18 samples (A) or from 34–82 cells (B) for each experimental group. Growth curves of these VSMCs from day 1 to day 7 (C, D). The cells were cultured either in a standard serum-supplemented medium (DMEM + FBS) or in a serum-free medium. Student t-test for unpaired data. Statistical significance: **p≤0.01 and ***p≤0.001 in comparison with Col.