Table 1.
Summary of the key functions of the two major categories of PUFAs during pregnancy.
Categories of PUFAs | Key Functions during Pregnancy | References |
---|---|---|
N-3 PUFAs | N-3 PUFAs and their derivatives exhibit potent anti-inflammatory properties | 7, 50-52, 190 |
Reduce the level of oxidative stress | 191, 192 | |
Promote fetal growth and reduce the risk of low birth weight infants | 9, 94 | |
Stimulate angiogenesis in the endometrium | 77, 78 | |
Promote the development of the nervous system and retina, and enhance cognitive function | 93, 193 | |
Improve insulin resistance | 51 | |
N-6 PUFAs | Regulate immune and inflammatory responses, primarily exerting pro-inflammatory effects, while lipoxins can exhibit anti-inflammatory properties | 16, 194 |
The derivatives 2-series PGs regulate the process of embryo implantation and uterine contractions | 58, 195 | |
Promote fetal weight gain and the proliferation of adipose tissue | 196, 197 | |
AA promote brain development by regulating cell division and signaling processes | 198 |