Skip to main content
. 2024 Nov 4;20(15):6018–6037. doi: 10.7150/ijbs.103404

Table 1.

Summary of the key functions of the two major categories of PUFAs during pregnancy.

Categories of PUFAs Key Functions during Pregnancy References
N-3 PUFAs N-3 PUFAs and their derivatives exhibit potent anti-inflammatory properties 7, 50-52, 190
Reduce the level of oxidative stress 191, 192
Promote fetal growth and reduce the risk of low birth weight infants 9, 94
Stimulate angiogenesis in the endometrium 77, 78
Promote the development of the nervous system and retina, and enhance cognitive function 93, 193
Improve insulin resistance 51
N-6 PUFAs Regulate immune and inflammatory responses, primarily exerting pro-inflammatory effects, while lipoxins can exhibit anti-inflammatory properties 16, 194
The derivatives 2-series PGs regulate the process of embryo implantation and uterine contractions 58, 195
Promote fetal weight gain and the proliferation of adipose tissue 196, 197
AA promote brain development by regulating cell division and signaling processes 198