Table 3.
Univariate and multivariate prognostic analysis.
| Variable | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| HR (95%CI) | p-value | HR (95%CI) | p-value | |
| Gender (male/female) | 1.018 (0.343~3.021) | 0.974 | ||
| Age | 1.038 (1.012~1.065) | 0.004 | 1.030 (1.002~1.059) | 0.034 |
| ECOG grade (1/0) | 1.280 (0.639~2.566) | 0.487 | ||
| HBV (presence/absence) | 1.418 (0.673~2.986) | 0.359 | ||
| Cirrhosis (presence/absence) | 1.167 (0.349~3.896) | 0.802 | ||
| Hyperbilirubinemia (presence/absence) | 0.630 (0.221~1.800) | 0.389 | ||
| Hypoproteinemia (presence/absence) | 0.939 (0.470~1.878) | 0.859 | ||
| Tumor Number (multiple/single) | 2.336 (1.126~4.848) | 0.023 | 2.219 (1.067~4.617) | 0.033 |
| Tumor Diameter (≥10cm/<10cm) | 1.302 (0.500~3.393) | 0.589 | ||
| PVTT (presence/absence) | 2.888 (1.244~6.705) | 0.014 | 2.478 (1.051~5.842) | 0.038 |
| Child-Pugh (B/A) | 1.786 (0.847~3.765) | 0.128 | ||
| AFP (≥400ng/mL/<400ng/mL) | 1.613 (0.800~3.251) | 0.181 | ||
| BCLC (A/C) | 1.877 (0.433~8.147) | 0.400 | ||
| BCLC (B/C) | 0.858 (0.350~2.103) | 0.738 | ||
HBV, hepatitis B virus; PVTT, portal vein tumor thrombus; AFP, alpha-fetoprotein; BCLC, barcelona clinic liver cancer.