Reagents and tools table
| Reagent/Resource | Reference or Source | Identifier or Catalog Number |
|---|---|---|
| Experimental Models | ||
| Patient samples | Sun Yat-sen University Cancer Center and Gastrointestinal and Anal Hospital of Guangdong Province | Tables EV2–3; Source data for Fig. 1 |
| Recombinant DNA | ||
| Antibodies | ||
| Oligonucleotides and other sequence-based reagents | ||
| Chemicals, Enzymes and other reagents | ||
| carnitine C16:0-d3 | Sigma-Aldrich | Cat#55107 |
| palmitic acid-d3 | Sigma-Aldrich | Cat#615951 |
| Cer d18:1-d7/18:0 | Avanti | Cat#860677P |
| LPC 17:0-d5 | Avanti | Cat#855679L |
| PC 17:0/22:4-d5 | Avanti | Cat#855678L |
| PE 17:0/17:0 | Avanti | Cat#830756P |
| SM d18:1/15:0-d9 | Avanti | Cat#860686P |
| TG 15:0/18:1/15:0-d5 | Avanti | Cat#860901P |
| Software | ||
| Mass Spectrometry-Data Independent Analysis (MS-DIAL) software (v4.9) | open access | |
| Analyst (v1.6) | AB SCIEX | |
| R software (v 4.0.5) | Open access | |
| mixOmics R package (6.14.1) | Rohart et al, 2017 | |
| caret R package (v 6.0-88) | Kuhn, 2021 | |
| pROC R package (Version 1.18.0) | Open access | |
| ConsensusClusterPlus R package (v 1.54.0) | Wilkerson and Hayes, 2010 | |
| ComplexHeatmap R package | Gu et al, 2016 | |
| survival R package (v 3.2-7) | Therneau, 2020 | |
| MetaboAnalyst (v.5.0) | Cardinal 2.14.0 | |
| Other | ||
| ACQUITY UPLC system | Waters | |
| tripleTOF™ 5600 plus mass spectrometer | AB SCIEX | |
| hybrid QQQ-linear ion trap mass spectrometer, Q-Trap 5500 system | AB SCIEX | |
| Q Exactive HF mass spectrometer | Thermo Fisher Scientific | |
| DGIdb database | Griffith et al, 2013 | |