TABLE 1.
Patient number | Age (years) | Height (cm) | Weight (kg) | Lymphoma histology and Ann Arbor stage | Chemotherapy scheme and frequency of application | Additional systemic therapy | Vincristine cumulative dose (mg/m2) |
---|---|---|---|---|---|---|---|
1 | 59 | 183 | 66.0 | DLBCL Stage IV A | R‐CHOP every 3 weeks | Rituximab (twice) | 3.78 |
2 | 55 | 170 | 115.0 | DLBCL Stage II A | R‐CHOP every 3 weeks | None | 2.71 |
3 | 51 | 179 | 83.0 | FBCL Stage I A | R‐CHOP every 2 weeks | None | 2.97 |
4 | 58 | 158 | 59.0 | PTCL Stage II AE | CHOP every 3 weeks | None | 5.03 |
5 | 71 | 180 | 85.0 | DLBCL Stage IV B | R‐CHOP every 3 weeks | None | 2.93 |
6 | 39 | 178 | 90.7 | DLBCL Stage IV B | R‐CHOP every 3 weeks | None | 2.93 |
7 | 44 | 182 | 85.0 | LBCL Stage IV A | R‐CHOP every 4 weeks | None | 6.76 |
8 | 71 | 183 | 106.0 | DLBCL Stage I A | R‐CHOP every 4 weeks | None | 5.36 |
9 | 43 | 181 | 90.0 | DLBCL Stage II A | R‐CHOP every 3 weeks | None | 3.79 |
10 | 69 | 184 | 95.0 | DLBCL Stage III A | R‐CHOP every 3 weeks | None | 2.74 |
11 | 55 | 163 | 67.0 | DLBCL Stage I BE | R‐CHOP every 3 weeks | None | 3.50 |
12 | 60 | 184 | 104.5 | DLBCL Stage I A | R‐CHOP every 3 weeks | None | 2.63 |
Median (patients) [IQR] | 56.5 [21.00] | 180.5 [11.0] | 87.5 [31.13] | n.a. | n.a. | n.a. | 3.3 [1.93] |
Median (controls) [IQR] | 49.5 [14.50], p = .163 | 172.5 [16.0], p = .203 | 81.8 [23.25], p = .198 | n.a. | n.a. | n.a. | n.a. |
Abbreviations: CHOP, Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone; DLBCL, diffuse large B‐cell lymphoma; FBCL, follicular B‐cell lymphoma; IQR, interquartile range; LBCL, large B‐cell lymphoma; n.a., not applicable; PTCL, peripheral T‐cell lymphoma; R‐CHOP, CHOP + Rituximab.