TABLE 2.
Results of high‐resolution nerve ultrasound, nerve conduction studies, and total neuropathy score in lymphoma patients treated with vincristine at different visits.
| Baseline | 3 weeks | 8 weeks | 6 months | |
|---|---|---|---|---|
| Median nerve CSA, carpal tunnel [mm2] (IQR) | 10.6 (3.8) | 10.9 (3.8) | 11.5 (3.7) | 10.9 (2.6) |
| Median nerve CSA, forearm [mm2] (IQR) | 7.7 (2.1) | 7.5 (2.5) | 7.7 (2.6) | 7.4 (3.6) |
| Median nerve CSA, upper arm [mm2] (IQR) | 9.6 (4.9) | 9.7 (3.1) | 10.9 (6.4) | 10.1 (3.4) |
| Ulnar nerve CSA, Guyon's canal [mm2] (IQR) | 6.1 (1.8) | 5.9 (2.3) | 6.4 (1.4) | 5.9 (1.5) |
| Ulnar nerve CSA, forearm [mm2] (IQR) | 7.2 (2.5) | 6.4 (2.7) | 6.8 (2.2) | 5.8 (1.4) |
| Ulnar nerve CSA, ulnar sulcus [mm2] (IQR) | 7.6 (3.4) | 8.3 (3.2) | 9.0 (3.5) | 8.1 (3.7) |
| Ulnar nerve CSA, upper arm [mm2] (IQR) | 8.0 (2.3) | 7.7 (3.5) | 8.4 (2.8) | 7.5 (1.8) |
| Radial nerve CSA, upper arm [mm2] (IQR) | 5.7 (2.7) | 5.2 (3.2) | 4.9 (2.0) | 5.0 (2.4) |
| Peroneal nerve popliteal fossa [mm2] (IQR) | 11.5 (6.3) | 13.0 (7.9) | 13.6 (3.4) | 11.4 (2.1) |
| Peroneal nerve fibular head [mm2] (IQR) | 12.3 (4.0) | 13 (5.4) | 14.4 (7.3) | 13.5 (5.7) |
| Tibial nerve CSA, popliteal fossa [mm2] (IQR) | 18.8 (5.6) | 20.0 (10.6) | 17.3 (6.8) | 19.0 (8.5) |
| Tibial nerve CSA, ankle [mm2] (IQR) | 11.8 (7.5) | 13.2 (10.2) | 14.3 (7) | 13.2 (5) |
| Sural nerve CSA [mm2] (IQR) | 3.2 (2) | 3.1 (2.1) | 3.2 (2.5) | 2.7 (1.5) |
| Sural nerve SNAP [µv] (IQR) | 8.9 (3) | 11.1 (10) | 6.9 (10) | 4.6 (5.3), p = .001 |
| Median nerve SNAP [µv] (IQR) | 16.9 (7.3) | 15.1 (10) | 13.9 (5.3) | 12.6 (6.9), p < .001 |
| Ulnar nerve SNAP [µv] (IQR) | 18.1 (11.9) | 12.7 (17.2) | 13.1 (16.7) | 10.6 (12.8), p < .001 |
| Radial nerve SNAP [µv] (IQR) | 5.1 (3.7) | 3.7 (3.2) | 4.7 (3.1) | 4.1 (3.0), p = .004 |
| Tibial nerve CMAP [mV] (IQR) | 12.1 (8.2) | 12.4 (6.6) | 12.9 (5.1) | 10.8 (9.7), p = .006 |
| TNS [points] (IQR) | 0 (0) | 0.5 (1) | 4 (2.5), p < .001 | 2 (2.5), p < .001 |
Note: N = 12. Median and the interquartile range (IQR) are indicated. The p‐values for Wilcoxon tests compared to baseline are indicated. Only significant p‐values are indicated.
Abbreviations: CMAP, compound muscle action potential; CSA, cross‐sectional area; SNAP, sensory nerve action potential; TNS, total neuropathy score.