Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jul 24;57(12):e13718. doi: 10.1111/cpr.13718

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2024 The Author(s). Cell Proliferation published by Beijing Institute for Stem Cell and Regenerative Medicine and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Premeiotic Eif2s2 deletion in oocytes impairs communication between oocytes and pregranulosa/epithelial cells. (A) Differential interaction number and strength among the four ovarian cell clusters in ovaries from Eif2s2 ^fl/fl and Eif2s2 ^cKO mice. The red and blue lines indicate increase or decrease of number or strength, respectively, in ovaries of Eif2s2 ^cKO mice compared to those in Eif2s2 ^fl/fl mice. (B) Circular plots demonstrating the communication probabilities of representative differentially changed ligand–receptor pairs between oocytes and pregranulosa/epithelial cells in Eif2s2 ^fl/fl and Eif2s2 ^cKO ovaries. (C and D) Heat maps showed outgoing (C) and incoming (D) communication patterns of oocytes and pregranulosa/epithelial cells clusters of Eif2s2 ^fl/fl and Eif2s2 ^cKO ovaries.