. 2024 Dec 9;14(12):e088072. doi: 10.1136/bmjopen-2024-088072

Table 2. Result of base-case analysis and deterministic sensitivity analyses.

	Mean cost	Mean effect (QALY)	Bootstrap difference, mean incremental cost (95% CI)	Bootstrap difference, mean incremental effect (95% CI)	ICER
Base-case analysis
LAPs	£1937	1.936	£533 (£52 to £984)	0.031 (−0.079 to 0.139)	£17 193
COCP	£2470	1.968	£533 (£52 to £984)	0.031 (−0.079 to 0.139)	£17 193
Deterministic sensitivity analysis
1. Undiscounted cost and outcome
LAPs	£2012	2.005	£466 (£−51 to £949)	0.032 (−0.086 to 0.146)	£14 562
COCP	£2477	2.037	£466 (£−51 to £949)	0.032 (−0.086 to 0.146)	£14 562
2. Partial societal perspective
LAPs	£4546	1.936	£773 (£229 to £1297)	0.031 (−0.079 to 0.139)	£24 935
COCP	£5319	1.968	£773 (£229 to £1297)	0.031 (−0.079 to 0.139)	£24 935
3. Including the cost of other types of surgery mentioned by participants (removal of fibroids, removal of polyps and endometrial ablation)
LAPs	£2006	1.936	£631 (£117 to £1128)	0.031 (−0.079 to 0.139)	£20 354
COCP	£2637	1.968	£631 (£117 to £1128)	0.031 (−0.079 to 0.139)	£20 354
4a. Subgroup analysis: LNG-IUS vs COCP
LNG-IUS	£2336	1.953	£135 (£−709 to £769)	0.015 (−0.090 to 0.176)	£9009
COCP	£2471	1.968	£135 (£−709 to £769)	0.015 (−0.090 to 0.176)	£9009
4b. Subgroup analysis: DMPA vs COCP
DMPA	£1619	1.924	£851 (£391 to £1,269)	0.044 (−0.091 to 0.180)	£19 232
COCP	£2471	1.968	£851 (£391 to £1,269)	0.044 (−0.091 to 0.180)	£19 232

COCPcombined oral contraceptives pillDMPAdepot medroxyprogesterone acetateICERincremental cost-effectiveness ratioLAPslong-acting progestogensLNG-IUSlevonorgestrel-releasing intrauterine systemQALYquality-adjusted life-year