Table 2.

Most significant features contributing to the regression models evaluating the efficacy of each antihypertensive medication in the RIGIPREV study. This table highlights the key features that provide the most information for each regression model, which represents the efficacy of different antihypertensive drugs, including angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers (BB), diuretics (DIU), and combinations.

Importance	ACEI	ARB	BB	DIU	DIU+ACEI	DIU+ARB
1	Weight	cfPWVa	TSHb	CAVIc	AIx75d	Basophils
2	HbA1ce	cLDLf	DBPg	Waist circumference	Uric acid	MPVh
3	ALT/SGPTi	AST/GOTj	cfPWV	Vitamin D	ABIk	MCVl
4	Creatinine	CHbCMm	HbA1c	cHDLn	LVH Cornello	LVH Cornell
5	baPWVp	Alx75	Albumin and creatinine	cLDL	HbA1c	DBP
6	Hemoglobin	Uric acid	cHDL	MPV	Triglycerides	Hematocrit
7	LVH Cornell	FPGq	Uric acid	Creatinine	cfPWV	TSH
8	cHDL	Total cholesterol	Triglycerides	RDWr	Height	cfPWV
9	Uric acid	GGTs	ABI	IMTt plaque	GGT	Monocytes
10	Red blood cell distribution width	eGFRu	eGFR	IMT	baPWV	IMT

^acfPWV: carotid-femoral pulse wave velocity.

^bTSH: thyroid-stimulating hormone.

^cCAVI: cardio-ankle vascular index.

^dAIx75: augmentation index at 75 mm Hg.

^eHbA_1c: glycated hemoglobin.

^fcLDL: low-density lipoprotein cholesterol.

^gDBP: diastolic blood pressure.

^hMPV: mean platelet volume.

ⁱALT/SGPT: alanine aminotransferase/serum glutamic pyruvic transaminase.

^jAST/GOT: aspartate aminotransferase/glutamic oxaloacetic transaminase.

^kABI: ankle-brachial index.

^lMCV: mean corpuscular volume.

^mCHbCM: mean corpuscular hemoglobin content.

ⁿcHDL: high-density lipoprotein cholesterol.

^oLVH Cornell: left ventricular hypertrophy diagnosed by Cornell.

^pbaPWV: brachial-ankle pulse wave velocity.

^qFPG: fasting plasma glucose.

^rRDW: red blood cell distribution width.

^sGGT: gamma-glutamyl transferase.

^tIMT: intima-media thickness.

^ueGFR: estimated glomerular filtration rate.