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Generation of transgenic mouse expressing optimized ATP8 from a safe harbor locus in the nucleus
Schematic of the oATP8 construct (A) and diagram portraying the ɸC31-mediated recombination of the oATP8 construct into the mouse ROSA26 locus (NC_000072.7::113052993) (B). An overview of the breeding scheme used to generate the experimental groups (C).
