Figure 5.

Single chamber Social Interaction (SI) test. (A) Schematic of SI test. (B) Light (or mock) activation timeline during SI test. (C–G) DG BlgC mice receiving photostimulation (cGMP) showed a significant increase in the total number of contacts (D) with a stranger mouse compared to controls. There were no significant differences between the two groups in the total duration of contact (C) and active contacts (E), mean duration per contact (F), and total distance traveled (G). Cntrl n = 5 pairs, cGMP n = 7 pairs. Data are mean ± SEM. Statistical analysis was performed using an unpaired t-test.