Table 1.
Demographic characteristics and PET scan parameters for nine healthy volunteers injected with [18F]SF51.
| Volunteer demographics and PET scan parameters | Whole-body |
Brain |
||
|---|---|---|---|---|
| MAB (n = 2) | HAB (n = 2) | MAB (n = 3) | LAB (n = 2) | |
| Male: Female (n) | 1:1 | 1:1 | 2:1 | 1:1 |
| Age (year) | 42 (8) | 43 (14) | 45 (9) | 47 (12) |
| Body weight (kg) | 58 (3) | 90 (24) | 69 (7) | 77 (1) |
| Injected activity (MBq) | 135 (83) | 191 (11) | 188 (8) | 190 (3) |
| Molar activity (MBq/nmol) a | 70 (12) | 76 (2) | 76 (7) | 78 (6) |
| Injected mass dose (nmol/kg) | 0.032 (0.016) | 0.029 (0.01) | 0.033 (0.002) | 0.032 (0.002) |
MAB: mixed-affinity binder; HAB: high-affinity binder; LAB: low-affinity binder.
a
Molar activity as reported at the time of injection; data are presented as mean values with SD in parentheses.