TABLE 2.

Evolution of percentage and duration of pain relief, global NPSI and sub‐score NPSI at baseline and during the first four sessions (mean ± SD).

	Baseline	Session 1	Session 2	Session 3	Session 4	b
Pain relief (%)
Whole population	–	12.0 ± 22.9	16.0 ± 23.3	21.6 ± 27.4	27.2 ± 28.0	4.55 [3.09;6.01]*
Responders	–	19.2 ± 26.6	25.6 ± 25.3	35.6 ± 27.8	41.4 ± 24.6	7.72 [5.58;9.85]*
Non‐responders	–	6.2 ± 18.0	6.8 ± 16.3	7.1 ± 18.2	8.7 ± 19.6	–
Duration of pain relief (d)
Whole population	–	3.2 ± 6.6	4.8 ± 7.0	6.6 ± 8.8	7.2 ± 7.7	1.21 [0.77;1.64]*
Responders	–	5.3 ± 8.0	8.1 ± 7.7	10.4 ± 9.0	11.0 ± 7.1	1.93 [1.26;2.61]*
Non‐responders	–	1.7 ± 6.4	1.7 ± 5.0	2.1 ± 5.5	2.1 ± 4.5	–
Global NPSI (/100)
Whole population	36.3 ± 17.7	38.8 ± 20.9	37.6 ± 20.9	38.1 ± 22.4	36.2 ± 22.5	+0.07 [−0.62;0.76]
Responders	37.0 ± 18.4	37.9 ± 22.5	35.2 ± 21.5	35.0 ± 22.7	32.3 ± 22.0	−1.25 [−2.08;‐0.41]*
Non‐responders	36.0 ± 16.8	38.6 ± 18.1	40.2 ± 19.7	40.7 ± 21.4	40.4 ± 22.9	–
Sub‐score NPSI (/10)
Whole population	6.9 ± 2.1	6.6 ± 2.4	6.2 ± 2.9	6.0 ± 2.7	5.9 ± 2.6	−0.28 [−0.41;−0.15]*
Responders	6.0 ± 2.2	6.3 ± 2.7	5.7 ± 3.1	5.4 ± 2.8	5.2 ± 2.6	−0.41 [−0.59;−0.24]*
Non‐responders	6.9 ± 1.9	7.1 ± 1.8	6.7 ± 2.3	6.4 ± 2.5	6.7 ± 2.5	–

Note: b[IC95] is the coefficient of linear regression estimated with LMMs. See Table S3 for more details on LMMs.

^*Bold values indicates significant test p < 0.001.