Figure 1.

Tabersonine is a hub of the monoterpene indole alkaloid (MIA) metabolism.

Characterized reactions from tabersonine are represented with solid arrows compared to dotted arrows for unknown reactions. Pink or green MIA names represent alkaloids from Catharanthus roseus or Tabernaemontana elegans, respectively. The position of each modified atom is annotated by a specific point color on the tabersonine and numbered with historical versions of numbering found in the enzymatic literature. 16OMT, 16 O‐methyltransferase; T3O, tabersonine 3‐oxygenase; T3R, tabersonine 3‐reductase; T16H, tabersonine 16‐hydroxylase; T19H, tabersonine 19‐hydroxylase; TAT, tabersonine acetyltransferase; TEX, tabersonine epoxidase.