Table 1.

Characteristics of donors with concordant-positive HIV infection, percentage of those infections that are recently acquired based on limiting antigen avidity testing, and multivariable model of factors associated with recently acquired HIV in these donors in the US from 2010-2018.

Donor Characteristic	Total N=1154	Recent n (%) n=317	p-value	Adjusted Odds of Recently Acquired Infection**
Donation History				Odds Ratio	95% CI
Repeat	384	149 (38.8)	< 0.001	2.21	1.65 – 2.94
First-time	770	168 (21.8)		Reference
Sex
Male	941	273 (29.0)	0.014	1.26	0.87 – 1.87
Female	213	44 (20.7)		Reference
Age Group
16-17	89	32 (36.0)	< 0.001	2.80	1.30 – 6.22
18-24	369	151 (40.9)		2.71	1.44 – 5.41
25-39	393	85 (21.6)		1.15	0.60 – 2.30
40-54	236	35 (14.8)		0.81	0.40 – 1.70
55+	67	14 (20.9)		Reference
Race
White/Caucasian	317	89 (28.1)	0.87	Reference
Black/African American	444	125 (28.1)		0.93	0.65 – 1.33
Asian	19	5 (26.3)		0.82	0.25 – 2.39
American Indian or Alaska Native	5	1 (20.0)		0.59	0.03 – 4.54
Other	27	7 (25.9)		1.21	0.42 – 3.21
Multiple	22	3 (13.6)		0.37	0.08 – 1.21
Unknown/Missing	320	87 (27.2)		1.22	0.77 – 1.94
Ethnicity*
Hispanic	179	48 (26.8)	0.023	0.57	0.32 – 1.03
Not Hispanic	248	85 (34.3)		Reference
Unknown/Missing	727	184 (25.3)		0.64	0.45 – 0.92
Region of the Country
Midwest	141	47 (33.3)	0.30	Reference
Northeast	180	51 (28.3)		0.88	0.53 – 1.47
South	647	177 (27.4)		0.79	0.52 – 1.20
West	158	35 (22.2)		0.57	0.32 – 0.99
Unknown or US Territories	28	7 (25.0)		0.74	0.25 – 1.98

^*Ethnicity was not available in our datasets for all TTIMS blood centers for the entire period. For Vitalant the percentage recent was not significantly different for Hispanic (11/46, 23.9%) and non-Hispanic 31/90, 34.4%) donors, p=0.289.

^**Multivariable model adjusts for all listed variables.