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. 2024 Jan 20;40(1):43–49. [Article in Chinese] doi: 10.3760/cma.j.cn501225-20231020-00125

表 1.

3组小鼠皮下埋植具有不同拓扑结构的三维生物打印海藻酸钠-明胶复合水凝胶支架7 d后支架周围组织中3种蛋白的表达比较(x±s

Comparison of the expressions of 3 proteins in the tissue surrounding the scaffolds of subcutaneously implanted three-dimensional bioprinted scaffolds of alginate-gelation composite hydrogels with different topological structures in 3 groups of mice after 7 days

组别 样本数 CD68 BMP-2 TNF
注:BMP-2为骨形态发生蛋白2,TNF为肿瘤坏死因子;T45、T60、T90中T指拓扑结构,45、60、90指三维生物打印支架时打印喷头的旋转角度;F值、P值为3组间各指标总体比较所得;P1值、P2值分别为T45组与T60组、T90组比较所得,P3值为T60组与T90组比较所得
T45组 3 23.9±2.0 6.1±0.5 15.4±3.5
T60组 3 63.8±12.5 17.5±0.8 8.0±0.9
T90组 3 25.4±2.2 2.4±0.9 15.4±2.3
F 27.58 177.60 8.95
P 0.001 < 0.001 0.016
P1 0.002 < 0.001 0.032
P2 > 0.999 0.003 > 0.999
P3 0.002 < 0.001 0.031