Table 3.
Postdischarge outcomes of interest for patients with Crohn’s disease hospitalized for intra-abdominal abscess stratified by route of discharge antibiotic.
| Univariate Analysis | Multivariable Analysisb | |||||
|---|---|---|---|---|---|---|
| PO Antibiotics (n = 74) | IV Antibiotics (n = 25) | OR (95% CI)d | P | OR (95% CI)c | P | |
| Abscess Recurrence (n, %) | 12 (16) | 5 (20) | 1.389 (0.432–4.469) | .58 | 1.901 (0.453–7.976 | .38 |
| Readmission for CD-related complication within 12 months (n, %) | 57 (77) | 10 (40) | 0.199 (0.076–0.523) | <.01 | 0.205 (0.062–0.679) | .01 |
| Reasons for nonsurgical CD-related readmission: | ||||||
| Readmission for additional course of antibiotics (n, %) | 18 (24) | 2 (8) | 0.271 (0.058–1.261) | .08 | 0.203 (0.036–1.137) | .07 |
| Readmission for IR drainage (n, %) | 19 (26) | 3 (12) | 0.395 (0.106–1.469) | .16 | 0.374 (0.086–1.627) | .19 |
| Readmission for small bowel obstruction (n, %) | 10 (14) | 3 (12) | 0.873 (0.220–3.463) | .94 | 0.93 (0.174–4.995) | .94 |
| Readmission for other Crohn’s complicationa (n, %) | 16 (22 | 4 (16) | 0.690 (0.207–2.302) | .55 | 0.574 (0.114–2.895) | .50 |
| Surgery (n, %) | 45 (61) | 19 (76) | 2.041 (0.729–5.714) | .17 | 2.550 (0.648–10.04) | .18 |
| Planned surgery (n, %) | 33 (45) | 12(48) | 0.623 (0.199–1.954) | .42 | 0.595 (0.154–2.302) | .45 |
| Unplanned surgery (n, %) | 12 (16) | 7 (28) | 1.604 (0.512–5.029) | .42 | 1.682 (0.434–6.512) | .45 |
| Readmission for postop complications (n, %) | 8 (11) | 2 (8) | 0.531 (1.01–2.793) | .45 | 0.661 (0.097–4.513) | .67 |
aDefined as admission for PICC line complication (ie, thrombosis, infection), IR drain site complication, persistent symptoms (poor oral intake, nausea, emesis, abdominal pain, etc), IV steroids, or Crohn’s disease flare.
bAdjusted for abscess size greater than 6 cm, history of prior surgery, history of penetrating disease, age, WBC on discharge, history of resistant strains.
cReference group is IV antibiotic group for analysis.