Table 3a:
UTI and urosepsis: matched-pair comparison between ADPKD patients and control group.
|
ADPKD
(n = 161) |
Control
(n = 161) |
OR a | 95%CI | P value | |
|---|---|---|---|---|---|
| Patients with UTI or urosepsis during initial hospitalization, n (%) | 14 (8.8) | 12 (8.2) | 1.09 | 0.49; 2.43 | .841 |
| Entire observation period | |||||
| Patients with UTI, n (%) | 63 (39.1) | 43 (26.7) | 1.81 | 1.09; 3.02 | .022 |
| UTI episodes per patient, mean ± SD | 0.8 ± 1.4 | 0.5 ± 1.1 | 1.68 | 1.27; 2.24 | <.001 |
| Patients with urosepsis, n (%) | 34 (21.1) | 28 (17.4) | 1.26 | 0.68; 2.33 | .456 |
| Urosepsis episodes per patient, mean ± SD | 0.3 ± 0.8 | 0.2 ± 0.5 | 1.49 | 0.96; 2.29 | .074 |
| Patients with UTI or urosepsis, n (%) | 71 (44.1) | 55 (34.2) | 1.65 | 0.99; 2.74 | .055 |
| UTI and urosepsis episodes per patient, mean ± SD | 1.1 ± 1.9 | 0.7 ± 1.4 | 1.63 | 1.28; 2.01 | <.001 |
Patients were censored from the time at which both native kidneys had been removed. In 22 ADPKD patients and in 9 control patients both native kidneys had been removed before Tx resulting in 161 matched pairs (in three pairs both native kidneys had been removed before Tx in both, the ADPKD patient and the control patient).
a
Odds ratio for ADPKD patients versus control patients estimated by a conditional logistic regression model adjusted for unilateral nephrectomy before Tx.
Abbreviations: ADPKD, polycystic kidney disease; CI, confidence interval; OR, odds ratio; SD, standard deviation; Tx, transplantation; UTI, urinary tract infection.