Table 2.
Summary of previously reported primary adrenal T/NK cell lymphoma cases
| Case | Age | Sex | Presenting symptoms | Site | Size | Adrenal function | Diagnosis | Pathology | Treatment | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|
| Schnitzer et al, 1986 |
74 | M | Fatigue, weight loss, fever |
Bilateral | 30 mm/ 40mm |
I | Biopsy | Diffuse large T-cell | No treatment | Early death |
| Oppong et al, 1991 |
63 | M | Weight loss, lethargy, abdominal pain |
Bilateral | NM | I | Biopsy | T-cell | Chemotherapy | Death 4 months later |
| Pimentel et al, 1997 |
42 | M | Vomiting, weight loss, fever |
Bilateral | NM | I | Biopsy | Diffuse large cleaved T-cell | Chemotherapy | Death 4 months later |
| May et al, 1998 |
59 | M | Asymptomatic | Right | NM | N | NM | Centroblastic T-cell | Surgery/radiation | Remission 8 years later |
| Nakatsuka et al, 2002 |
67 | M | Asymptomatic | Left | 110mm | I | Surgery | Peripheral T-cell, not specified | Surgery | Remission 10 months later |
| Nakatsuka et al, 2002 |
74 | M | Fatigue, fever | Bilateral | NM | NM | Autopsy | Peripheral T-cell, not specified | No treatment | Death 33 months later |
| Xu et al, 2003 |
NM | NM | Lumber pain, weight loss, fever |
Bilateral | NM | N | NM | T-cell | Surgery | Death within 3 months |
| Mizoguchi et al, 2005 |
17 | M | Fever, general fatigue | Bilateral | 48 mm/ 50mm |
NM | Autopsy | Nasal-type NK-cell | No treatment | Death 1 week later |
| Tomoyose et al, 2007 |
37 | F | Back pain, malaise, fever |
Bilateral | 92 mm/ 92mm |
N | Biopsy | ATLL | Chemotherapy | Death 11 months later |
| Sfaxi et al, 2008 |
70 | M | Anorexia, weight loss, fever |
Bilateral | 120 mm/ 74mm |
I | Surgery | T-cell lymphoma | Surgery | Death 4 days later |
| Tsukahara et al, 2012 |
79 | F | Cough, bloody sputum | Bilateral | 57 mm/ 74mm |
NM | Autopsy | Nasal-type NK-cell | No treatment | Death 11 days later |
| Bommannan et al, 2017 |
26 | M | Weight loss, blurred vision |
Bilateral | 93 mm/ 92mm |
N | Biopsy | T-cell | No treatment | Early death |
| Bedaiwi et al, 2020 |
71 | M | Anorexia, weight loss, eye pain |
Left | NM | NM | Biopsy | T-cell lymphoma | Chemotherapy | Death within 1 year |
| Frankel et al, 2000 |
62 | M | Fatigue | Bilateral | 150 mm/ 40mm |
NM | Biopsy | Anaplastic large cell | Surgery/ Chemotherapy |
Remission 23 months later |
| Our case | 64 | M | Weight loss, fever, anorexia, fatigue | Left | 75mm | N | Biopsy | Anaplastic large cell | Chemotherapy | Death 10 months later |
Abbreviations: ATLL, adult T-cell leukemia/lymphoma; I, insufficiency; N, normal; NK, natural killer; NM, not mentioned.