Disease	Pancreatic cancer
Stage of disease/treatment	Patients with adenocarcinoma of the pancreas who will receive chemotherapy with albumin-bound paclitaxel plus gemcitabine containing combination. The treatment in this study is investigational hand therapy intervention (Investigational Group) compared with a traditional occupational therapy approach (Traditional Group). Refer to Figures 1, 2, 3
Prior therapy	Not specified
Type of study	Pilot, double-blind, randomized clinical trial
Primary endpoint	To determine if hand therapy intervention targeting the nervous system can prevent or delay the time to onset of any grade of CIPN of the hands as measured by NCI CTCAE 4.0 and Patient Reported Outcomes as compared to traditional occupational therapy intervention
Secondary endpoints	To determine whether provocative testing of the upper extremity identifies/predicts patients at risk for CIPN To identify whether scores on the TEN TEST and the QuickDASH correlate to the Common Terminology Criteria for Adverse Events, version 4 (CTCAE-4.0) grades of peripheral neuropathy of the hands in patients who develop CIPN