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. 2024 Nov 27;14:1412027. doi: 10.3389/fonc.2024.1412027

Table 3.

Factors associated with OS and BCSS in a Cox proportional hazards model of patients diagnosed with early breast cancer in 2018,2019, and 2020.

Characteristics OS BCSS
95% CI 95% CI
HR Low High P HR Low High P
Race
White Reference Reference
Black 1.312 1.197 1.438 <0.001 1.174 1.029 1.339 0.017
Other 0.696 0.611 0.793 <0.001 0.743 0.617 0.894 0.002
Age
<50 Reference Reference
50≤;<70 1.531 1.363 1.72 <0.001 1.179 1.024 1.358 0.022
≥70 4.048 3.606 4.544 <0.001 2.37 2.045 2.748 <0.001
Grade
I Reference Reference
II 1.161 1.042 1.293 0.007 1.768 1.385 2.257 <0.001
III 1.595 1.412 1.802 <0.001 2.974 2.313 3.824 <0.001
Subtype
HR+/Her2- Reference Reference
HR+/Her2+ 0.987 0.866 1.126 0.848 0.781 0.634 0.962 0.02
HR-/Her2+ 1.152 0.984 1.348 0.078 1.013 0.816 1.256 0.91
HR-/Her2- 1.444 1.312 1.59 <0.001 1.555 1.371 1.764 <0.001
Stage
I Reference Reference
II 2.472 2.241 2.727 <0.001 4.366 3.714 5.133 <0.001
III 7.348 6.683 8.078 <0.001 17.644 15.16 20.536 <0.001
Radiation
No Reference Reference
Yes 0.341 0.317 0.367 <0.001 0.366 0.329 0.407 <0.001
Chemotherapy
No Reference Reference
Yes 0.773 0.708 0.844 <0.001 0.935 0.822 1.063 0.305
Year of diagnosis
2020 Reference Reference
2018 0.861 0.743 0.996 0.045 1.001 0.791 1.267 0.994
2019 0.887 0.766 1.026 0.105 0.998 0.789 1.262 0.985