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. 2024 Nov 27;14:1412027. doi: 10.3389/fonc.2024.1412027

Table 4.

Factors associated with OS and BCSS in a modified Cox proportional hazards model of patients diagnosed with early breast cancer in 2018, 2019, and 2020.

Characteristics OS BCSS
95% CI 95% CI
HR Low High P HR Low High P
Race
White Reference Reference
Black 1.381 1.207 1.58 <0.001 1.33 1.093 1.618 0.004
Other 0.683 0.561 0.833 <0.001 0.719 0.535 0.966 0.028
Age
<50 Reference Reference
50≤;<70 2.032 1.675 2.464 <0.001 1.443 1.13 1.842 0.003
≥70 5.251 4.338 6.357 <0.001 3.443 2.693 4.401 <0.001
Grade
I Reference Reference
II 1.185 1.004 1.397 0.045 1.766 1.215 2.565 0.003
III 1.557 1.294 1.875 <0.001 2.666 1.814 3.919 <0.001
Subtype
HR+/Her2- Reference Reference
HR+/Her2+ 1.326 1.105 1.592 0.002 0.987 0.729 1.337 0.933
HR-/Her2+ 1.365 1.089 1.712 0.007 1.107 0.797 1.538 0.544
HR-/Her2- 1.555 1.345 1.799 <0.001 1.544 1.269 1.88 <0.001
Stage
I Reference Reference
II 2.48 2.145 2.868 <0.001 4.729 3.687 6.066 <0.001
III 6.789 5.894 7.819 <0.001 18.161 14.376 22.942 <0.001
Radiation
No Reference Reference
Yes 0.199 0.175 0.225 <0.001 0.191 0.158 0.231 <0.001
Chemotherapy
No Reference Reference
Yes 0.772 0.678 0.879 <0.001 0.943 0.78 1.141 0.546
Year of diagnosis
2020 Reference Reference
2018 0.842 0.723 0.981 0.027 0.945 0.74 1.208 0.652
2019 0.912 0.786 1.06 0.231 1.055 0.83 1.341 0.663