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. 2024 Nov 20;56(12):2753–2762. doi: 10.1038/s41588-024-01988-0

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Extended Data Fig. 2 — a, Top: percentage of donors that have >1 cell with chromosome arm gained per cell type. Bottom: percentage of cells with gains per cell type (n = 12 basal samples, n = 26 luminal samples), each data point is a donor. b, Top: percentage of donors that have >1 cell with chromosome arm lost per cell type. Bottom: percentage of cells with losses per cell type (n = 12 basal samples, n = 26 luminal samples); each data point is a donor. Stars indicate p-values from two-sided Wilcoxon rank-sum test: ***p < 0.001, **p < 0.01, *p < 0.05. When no star is shown above comparisons, differences are not significant (p > 0). Box plots indicate the median, first and third quartiles (hinges) and the most extreme data points no farther than 1.5× the IQR from the hinge (whiskers). No adjustments for multiple comparisons were performed.