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. 2024 Jan 25;42(12):1888–1898. doi: 10.1038/s41587-023-02107-w

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 6 — a, (top) Representative epifluorescence images of Beas2B cells expressing GFP-tagged EML4-Alk v1 and immunostained for hits identified in the mass spectrometry analysis. Arrows indicate co-localization of EML4-Alk v1 with probed protein. (bottom) Colocalization analysis (n = 3 biologically independent experiments per condition). b, Representative immunoblot of Beas2B cells transfected with V5-tagged EML4-Alk v1 full length or with trimerization domain deleted (∆TD), subjected to V5 immunoprecipitation, and probed for hits identified in the MS analysis. Bar graphs represent mean ± s.e.m.