Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Nov 25;56(12):2790–2803. doi: 10.1038/s41588-024-01999-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Extended Data Fig. 3 — a Karyotype heatmap of 76 single cells arranged using Ward’s method for hierarchical clustering of structural variant genotypes in CK282. Examples of subclone-specific structural variants are labelled in the heatmap. b Strand-specific read depth of two representative single cells from CK282 showing a normal chromosome 8 (reference, top) and a complex genetic rearrangement comprising of two inverted duplications (InvDups), three deletions (Dels) and one larger InvDup, spanning the whole chromosome 8 (bottom). Reads denoting somatic structural variants, discovered using scTRIP, mapped to the Watson (orange) or Crick (green) strand. Del: Deletion, Dup: Duplication, Inv: Inversion, Tra: Translocation, Inter: Interstitial, Ter: Terminal, Chr: Chromosome, CF: Cell fraction, SV: Structural variant.