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. 2024 Nov 25;56(12):2790–2803. doi: 10.1038/s41588-024-01999-x

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 2 — a Strand-specific read depth of representative single cells from CK349 showing different rearrangements detected at chromosome 13 in different subclones. Reads denoting somatic structural variants, discovered using scTRIP, mapped to the Watson (orange) or Crick (green) strand. b Stacked barplot showing the cell fraction of different rearrangements detected at chromosome 13 in CK349 at diagnosis. The number of cells is indicated on top of the bar and the distinct rearrangements are labelled below. CF: Cell fraction, SV: Structural variant, Chr: Chromosome, Dup: Duplication, Del: Deletion, Ter: Terminal, CN: Copy number, WT: Wild-type, bp: Break point.