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. 2024 Nov 27;15:1465185. doi: 10.3389/fimmu.2024.1465185

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Copyright © 2024 Nakabo, Sandoval-Heglund, Hanata, Brooks, Hoffmann, Zhang, Ambler, Manna, Poncio, Hasni, Islam, Dell’Orso and Kaplan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation between clinical parameters and BMAL1 expression level in human SLE peripheral blood neutrophils. Correlation between BMAL1 mRNA expression in peripheral blood neutrophils from human SLE patients (n= 24) and SLEDAI (A), serum anti-ds DNA level (B), serum C3 level (C), serum C4 level (D), and daily dose of oral prednisone (PDN) (E). (F) Correlation between BMAL1 expression in peripheral blood mononuclear cells (PBMCs) and neutrophils. The statistical analysis was done using Spearman’s rank correlation coefficient for correlation analyses.