Table 1.
The characteristics of the enrolled subjects
| Variables | Non-sarcopenia (n = 323) | Sarcopenia (n = 449) | P |
|---|---|---|---|
| Age, years | 75.0 (71.0–80.0) | 77.0 (70.0–82.0) | 0.014 |
| Male, n (%) | 164 (50.8) | 245 (54.6) | 0.333 |
| BMI, kg/m2 | 25.18 (23.18–27.17) | 22.25 (19.90–23.89) | < 0.001 |
| Smokers, n (%) | 40 (12.4) | 63 (14.0) | 0.578 |
| Drinkers, n (%) | 32 (9.9) | 49 (10.9) | 0.741 |
| Hypertension, n (%) | 145 (44.9) | 186 (41.4) | 0.375 |
| Diabetes, n (%) | 38 (11.8) | 89 (19.8) | 0.004 |
| FBG, mmol/L | 5.50 (5.10–6.05) | 5.62 (5.18–6.55) | 0.008 |
| ALT, U/L | 16.24 (12.25–22.10) | 14.70 (10.91–19.68) | 0.001 |
| AST, U/L | 21.80 (19.0–27.0) | 21.76 (18.02–26.94) | 0.374 |
| TBil, μmol/L | 13.17 (10.70–16.65) | 12.20 (9.20–15.71) | 0.001 |
| SCr, μmol/L | 67.25 (53.22–81.94) | 68.50 (52.65–84.3) | 0.482 |
| BUN, mmol/L | 5.42 (4.53–6.27) | 5.68 (4.62–6.98) | 0.004 |
| TC, mmol/L | 4.78 (4.21–5.46) | 4.91 (4.29–5.47) | 0.350 |
| TG, mmol/L | 1.40 (1.04–1.90) | 1.15 (0.88–1.66) | < 0.001 |
| LDL-C, mmol/L | 2.40 (1.86–2.87) | 2.41 (1.87–3.00) | 0.428 |
| HDL-C, mmol/L | 1.39 (1.22–1.58) | 1.48 (1.24–1.74) | < 0.001 |
| hs-CRP, mg/L | 2.06 (1.68–4.03) | 4.82 (1.93‐6.23) | < 0.001 |
| Metrnl, pg/mL | 211.9 (163.2–270.0) | 180.1 (151.3–220.3) | < 0.001 |
| Grip, kg | 27.30 (22.20–33.10) | 17.80 (15.40–24.30) | < 0.001 |
| Males | 33.10 (29.60–36.20) | 23.80 (20.60–26.10) | < 0.001 |
| Females | 22.20 (19.70–24.70) | 15.60 (13.33–16.70) | < 0.001 |
| Gait speed, m/s | 1.06 (0.98–1.16) | 0.90 (0.79–1.04) | < 0.001 |
| Males | 1.00 (1.00–1.19) | 0.91 (0.80–1.04) | < 0.001 |
| Females | 1.06 (0.98–1.13) | 0.90 (0.74–1.01) | < 0.001 |
| ASMI, kg/m2 | 7.08 (6.32–7.60) | 5.64 (5.20–6.48) | < 0.001 |
| Males | 7.56 (7.14–7.99) | 6.29 (5.91–6.71) | < 0.001 |
| Females | 6.34 (6.00–6.86) | 5.19 (4.79–5.48) | < 0.001 |
ALT alanine transaminase, ASMI appendicular skeletal muscle mass index, AST aspartate aminotransferase, BMI body mass index, BUN blood urea nitrogen, FBG fasting blood glucose, HDL-C high-density lipoprotein cholesterol, hs-CRP hypersensitive C-reactive protein, LDL-C low-density lipoprotein cholesterol, Metrnl Meteorin-like, Scr serum creatinine, TBil total bilirubin, TC total cholesterol, TG triglyceride