Table 4. Embryologic and pregnancy outcomes of PCOS patients by total testosterone levels: upper 50% (1.6-5.6 nmol/L) vs. lower 50% (0.30-1.50 nmol/L).
Variable |
Lower 50% TT, (n=32) |
Upper 50% TT, (n=35) |
p-value |
Number of oocytes collected |
27.5±7.5 |
28.3±9.7 |
0.73 |
Number of MII oocytes |
20.5±6.9 |
20.4 3±8.3 |
0.98 |
MII fertilized (%) |
73.3±18.8 |
73.5±16.7 |
0.96 |
2PN grew to blastocyst (%) |
48.3±22.9 |
52.5±27.5 |
0.50 |
MII grew to blastocyst (%) |
34.1±17.0 |
38.2±19.1 |
0.36 |
Number of embryos frozen |
6.9±4.0 |
8.1±5.7 |
0.32 |
Clinical pregnancy no. (%) |
15 (46.8) |
15 (42.8) |
0.90 |
Miscarriage no/total pregnancies (%) |
10/22 (45%) |
9/18 (50%) |
0.77 |
Live birth no. (%) |
12 (37.5) |
9 (25.7) |
0.33 |
Data are presented as mean ± standard deviation, PCOS: Polycystic ovary syndrome, TT: Total testosterone, LH: Luteinizing hormone, MII oocytes: Mature oocytes, 2PN: 2 pronuclei stage