Figure 2.

Metformin improved radiation-induced pathological changes in the lungs. (A) Representative images of hematoxylin-eosin staining and the comparison of pathological scores, a: alveolus, as: alveolar septa, red arrow: alveolar hemorrhage; (B) Representative images of Masson’s Trichrome staining and the comparison of fibrotic scores, black arrow: thickening of alveolar septa. The results are presented as mean ± SD. ^a P < 0.05 vs Control group, ^b P < 0.01 vs Control group, ^c P < 0.05 vs IR group, ^d P < 0.01 vs IR group, ^e P < 0.05 vs L-Met group.